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Sydney Padgett - Spartans Illustrated

Michigan State vs. Louisville: The matchups, the pressure points, and what decides it

Where the Spartans have the edge – and where it can get dangerous

By Matt Sheehan
Published on March 21, 2026

I’m not going to sit here and tell you I feel great about this game.

I feel better than I did a few days ago. I feel better than I did when the bracket first dropped and I saw Louisville sitting there as the opponent, a team that can absolutely light you up from three and has just enough chaos baked into their DNA to ruin your weekend.

But feeling “better” and feeling “good” are two very different things, and if you’ve watched this Michigan State team all season, you already know why.

Because this is the kind of game where everything makes sense – until it doesn’t.

On paper, this should lean Michigan State.

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